姓 名：刘臣

管理类别：教学科研系列

所在单位：茶学系

学 位：Doctor of Philosophy（Wageningen University，2022年）

职 称：讲师

导师类别：

主要研究领域：茶源活性物质的营养机制研究；基于生理的药代动力学模型（PBPK）构建与应用

主要学习经历：

2011.09-2015.06， 西北农林科技大学 森林资源保护与游憩专业，本科

2015.09-2018.06， 中国农业科学院 植物保护研究所 农业昆虫与害虫防治专业，硕士

2018.11-2022.06， Wageningen University, Department of Toxicology，博士

2022.08-至今， williamhill威廉希尔官网茶学系任教

主要业绩：

1.Chen Liu^*,§,†, Jolijn van Mil^†, Annelies Noorlander^†, Ivonne M.C.M. Rietjens^†. Use of Physiologically Based Kinetic Modeling-Based Reverse Dosimetry to Predict In Vivo Nrf2 Activation by EGCG and Its Colonic Metabolites in Humans. Journal of Agricultural and Food Chemistry. 2022, accepted.

2.Chen Liu^1,2,*, Sjef Boeren³, Ignacio Miro Estruch²and Ivonne M. C. M. Rietjens². The Gut Microbial Metabolite Pyrogallol Is a More Potent Inducer of Nrf2-Associated Gene Expression Than Its Parent Compound Green Tea (-)-Epigallocatechin Gallate. Nutrients. 2022, 14, 16.

3.Chen Liu¹*, Sjef Boeren²and Ivonne M. C. M. Rietjens¹. Intra- and Inter-individual Differences in the Human Intestinal Microbial Conversion of (-)-Epicatechin and Bioactivity of Its Major Colonic Metabolite 5-(3′,4′-Dihydroxy-Phenyl)-γ-Valerolactone in Regulating Nrf2-Mediated Gene Expression. Frontiers in Nutrition. 2022, 9, 910785.

4.Xue Yao^a,1, Chen Liu^b,1(共一), Yunpeng Duan^a, Shiheng An^a, Jizhen Wei^a,*, Gemei Liang^b,*. ABCC2 is a functional receptor of Bacillus thuringiensis Cry1Ca in Spodoptera litura. International Journal of Biological Macromolecules. 2022, 194, 9-16.

5.Chen Liu^,*Jacques Vervoort, Joris van den Elzen, Karsten Beekmann, Marta Baccaro, Laura de Haan, and Ivonne M. C. M. Rietjens. Interindividual Differences in Human In Vitro Intestinal Microbial Conversion of Green Tea (-)-Epigallocatechin-3-O-Gallate and Consequences for Activation of Nrf2 Mediated Gene Expression. Molecular Nutrition & Food Research. 2021, 65, 2.

6.Chen Liu^,*Jacques Vervoort, Karsten Beekmann, Marta Baccaro, Lenny Kamelia, Sebas Wesseling, and Ivonne M. C. M. Rietjens. Interindividual Differences in Human Intestinal Microbial Conversion of (−)-Epicatechin to Bioactive Phenolic Compounds. Journal of Agricultural and Food Chemistry. 2020, 68, 48.

7.刘臣¹，张丹丹¹，王泽宇¹，陈琳¹，李国平²，梁革梅¹.棉铃虫对不同Bt蛋白的抗性及交互抗性研究.应用昆虫学报. 2018, 55, 01.

8.刘臣，陈琳，王冰洁，赵曼，梁革梅，郭予元.四种Bt蛋白对六种重要鳞翅目害虫的杀虫活性评价.中国生物防治学报. 2017, 33, 06